hrp0086p1-p468 | Fat Metabolism and Obesity P1 | ESPE2016

Association of Fasting Triglycerides to High-Density Lipoprotein Ratio with Risk for Metabolic Disorders in Children

Efthymia Katsa Maria , Ioannidis Anastasios , Zyga Sofia , Sachlas Athanasios , Tsironi Maria , Paola Rojas Gil Andrea

Background: Atherosclerosis begins in childhood and progresses silently. Triglycerides/HDL ratio(TG/HDL) is a risk factor for cardiovascular diseases.Objective and hypotheses: To investigate TG/HDL as possible predictive factor for metabolic disorders in children.Method: Descriptive correlation, with 110 children (6–12 years old) in Sparta, Greece. Anthropometric and biochemical analyzes were performed.R...

hrp0095p1-436 | Diabetes and Insulin | ESPE2022

Association of the apoptotic markers Apo1/Fas and cCK-18 and the adhesion molecule ICAM-1 with Type 1 diabetes mellitus in children and adolescents.

Kostopoulou Eirini , Efthymia Katsa Maria , Ioannidis Anastasios , Foti Maria , Dimopoulos Ioannis , Spiliotis Bessie , Paola Rojas Gil Andrea

Introduction: Type 1 diabetes mellitus (T1DM) is characterized by insulin-producing pancreatic β-cells loss. Apo1/Fas, a glycosylated surface protein, is implicated in maintaining homeostasis of the immune system. Cytokeratin-18 (cCK-18) is a predictive marker of liver disorders in T2DM. Intercellular adhesion molecule-1 (ICAM-1) is considered a candidate gene for susceptibility to diabetes mellitus. Aim: To investigate the possible role of Apo1/Fas, cCK-...